Osteogenesis imperfecta - Wikipedia - medical photos adult osteogenesis imperfecta


Osteogenesis Imperfecta | OI | MedlinePlus medical photos adult osteogenesis imperfecta

The Adult Health Initiative: Working to Improve the Health and Well-being of Adults with Osteogenesis Imperfecta. The Adult Health Initiative is a multi-year effort sponsored by the OI Foundation. It is a series of research projects, publications, and outreach efforts to OI Adults and their Physicians.

During the Adult Years. Introduction Osteogenesis imperfecta (OI) is a genetic disorder characterized by bones that break easily, often from little or no apparent trauma. It is caused by a genetic defect that affects the body’s production of type I collagen, which is the major protein in connective tissue.

The name osteogenesis imperfecta dates to at least 1895 and has been the usual medical term in the 20th century to present. The current four type system began with Sillence in 1979. An older system deemed less severe types "osteogenesis imperfecta tarda" while more severe forms were deemed "osteogenesis imperfecta congenita."Causes: Genetic (autosomal dominant, new mutation).

Osteogenesis imperfecta, also known as brittle bone disease, is a genetic disorder that causes bones to break easily without cause. The condition affects the body's ability to produce collagen, a protein in the body's connective tissue.